Lose pigmentation Melanin

Lose pigmentation Melanin - Professional Look

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Lose pigmentation Melanin - melanin in the skin lacks Vitiligo (from Lat. Nakozhnaya vitiligo, a disease that lichen) condition in which the skin loses melanine, pigment that determines the color of skin, hair and eyes. If the cells that produce melanine, die or are no longer form melanine, then appear on the skin slowly growing white lots of wrong forms Lose pigmentation Melanin.

The goal of treatment for Vitiligo is to try to restore the color of the skin (pigments) and improve its appearance. Depending on the type of therapy, Treatment of Vitiligo can take from 6 to 18 months. The choice of treatment depends on the way the number of white stations, and how widely they are distributed in the skin. Everyone reacts differently to treatment, so people are not at all valid specific therapy.

Vitiligo usually manifests itself as small spots, which are becoming more distributed, and over time. These changes in the skin can bring trouble from the point of view of the outside appearance of the body Lose pigmentation Melanin.

There is no specially designed method of treatment for Vitiligo. The goal of treatment is to stop or slow down the progression of skin depigmentatsii and try to restore the old color Lose pigmentation Melanin.

Gilchrest, Barbara A. (Brookline, MA, US)

Lose pigmentation Melanin - Details

Melanin is a special pigment that gives the skin and hair its natural color. It makes the skin tanned, but also produces unwanted freckles, birthmarks and other colored marks on the body.

Lose pigmentation Melanin - More Details

With humans melanin forms in special sea-star shaped cells called melanocytes in the basal layer of epidermis and then transforms into granules where pigments are combined with protein. Melanocytes inject melanin grains into the cells of the upper skin layer (cortical layer of the hair and the iris of the eye) and determine their color.

Lose pigmentation Melanin - Doctors view

Doctors from time to time state that tea, coffee, chocolate and cacao are harmful for our health. However, it is no good to give up these products once and for all as they contain melanin that is essential for the human organism. Also prunes, bilberry or dark grapes are good protection against cancer, sunburns and influence of radiation.

Signs and symptoms - The main sign of the loss of pigment-Lose pigmentation Melanin, which produces a milky stations (Lose pigmentation Melanin) on the skin. Other, less common signs may include:
- Premature or outdoor fallout of hair on the head, eyelash, eyebrows or beard
- Loss-colored tissues, which are on the inside of the mouth (mucous membranes membranes)
- Loss or change the color of the eye retina and Lose pigmentation Melanin

While any part of the body may be affected Lose pigmentation Melanin, depigmentatsiya usually develops first on the areas of the skin that are more susceptible to ingress of sunlight. This is part of the body, such as: the arms, legs, face and especially lips. Lose pigmentation Melanin usually manifests itself in one of three types:
- Focal. Depigmentatsiya limited to the area of one or more bodies.
- Segmentalny. Loss of color only on one side of his body.
- Synthesized. The loss of pigment widely distributed in all parts of the body.

Although the disease can occur at any age but Lose pigmentation Melanin usually appears between the ages of 20 to 30 years. White plots may have accrued on the face, in the region of the eye or on the neck, Lose pigmentation Melanin, elbow, genitals, hands or knees. They often can be symmetrical and spread all over the body. The disease can affect everyone, regardless of sex, age, race or color.

Most people with Lose pigmentation Melanin consider themselves fully healthy, and do not feel any unpleasant sensations. However, this condition is most often applies in people with certain autoimmune diseases, diseases in which the immune system reacts to the body's own organs. For example Addison's disease, the lack of vitamin B-12 (pernicious anemia), or problems with the thyroid gland, including hypothyroidism.

Arrangements for the distribution of Lose pigmentation Melanin is difficult to predict. Sometimes stains cease formed without treatment. In other cases, the loss of pigment may spread to the whole body.

Causes - Human skin consists of three layers - epidermis, the skin and subcutaneous tissue. The most distant layer of skin is the outer skin. Melanin - pigment that determines the color of skin, hair and eyes, is generated in the epidermis. Melanin exercises skin color and helps protect it against damage from ultraviolet rays.

People of all races born with approximately equal number of pigment cells. The rule, which melanin granules are formed in these cells and their concentration in the epidermis, is the inherited characteristics and the main factors in different color. When melanin not be part of the skin becomes white. When a white station is growing or spreading, can be a cause of Lose pigmentation Melanin.

The exact cause of Vitiligo is not known. Doctors and scientists are trying to put forward the theory that can cause the disease. This can be due to Lose pigmentation Melanin.

Gordon, Philip R. (Philadelphia, PA, US)

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Lose pigmentation Melanin - Good Hair

Having a good hair day doesn’t just happen by chance. It happens when taking care of your hair becomes just as important as taking care of your skin. But what do you do when your hair has been damaged by every day styling, and chemical processing, dyeing or perming? Is there any solution for fly-away hair, dullness and faded color?

Lose pigmentation Melanin - Science view

The color of hair is determined by the amount of melanin in the cortical layer. Dark hair has a lot of pigment while fair hair has fewer granules that are of smaller size. Diffusive or non-granulated melanin makes the hair red. Hair, like any other part of the body, requires essentials nutrients for growth and survival.

Lose pigmentation Melanin - Good Skin

When summer looms, many people start considering the best way to get that sun-bronzed glow — turning to self-tanners, tanning booths, a stretch in the sun, or a combination of these.

Lose pigmentation Melanin - Science view

But before you go into a tanning booth — spend a few minutes finding out about your skin and sun exposure. These facts can help you get the look you want without stressing your skin.

Lose pigmentation Melanin - More Details

Melanin is the body's way of protecting skin from burning. Darker-skinned people tan more deeply than lighter-skinned people because their melanocytes produce more melanin. But just because a person doesn't burn does not mean that he or she is also protected against skin cancer and other problems.

Lose pigmentation Melanin - See more

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Lose pigmentation Melanin - People view

Albinos, etc., that is no melanin and Lose pigmentation Melanin. "Dilution" pigment in Lose pigmentation Melanin happening because of inadequate normal number melanosom melanizatsii (110115). When tirozinazo-negativnom type glazo-kozhnogo albinizma this is due to the total absence tirozinazy, while other forms of this enzyme is present in the body, but does not operate with sufficient efficiency (88). According to the Witkop, has found no evidence of melaninoobrazovaniya inhibitors, and the level and variety of incentives tirozina hormones were within the norm Lose pigmentation Melanin. At the same time, ocular albino is the result of a reduced number of eye Lose pigmentation Melanin.
Identification of options Lose pigmentation Melanin based on the genetic, biochemical and histological criteria. But it is not always possible Lose pigmentation Melanin from one type to another in the face of the clinic. Lose pigmentation Melanin can be allotted 2 most common type glazo-kozhnogo albinizma (using test lukovitse hair). The first of these is described Kugelman and Wan-Scott in 1961 g (76). In conducting this test Lose pigmentation Melanin hair bulbs in a buffer solution tirozina over 24 hours, and then studied. During the incubation hair bulbs some albinos do not generate a pigment (that is demonstrated by the complete absence of the enzyme tirozinazy), while in other albinos onion growing concentration of melanin found. These forms are classified as tirozinazo-negativny albino and Lose pigmentation Melanin albino respectively, on the latest figures (104), tirozinazo-negativny albino, in turn, is divided into type 1-A, in which the enzyme activity completely missing, and type 1-B, in which the enzyme activity decreased significantly (so-called "yellow" type). This biochemical analysis feasible only in patients older than 5 years. In 1976, a test has been upgraded King and Witkop Lose pigmentation Melanin, it was included to quantify the activity of a single hair tirozinazy lukovitse. Van Dorp and sponsors in Lose pigmentation Melanin significantly increased both biochemical tests and assumed that would be more correct tirozinazo-pozitivny glazo-kozhny albino depending on the category of Lose pigmentation Melanin availability.

Lose pigmentation Melanin - More Details

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Lose pigmentation Melanin - Science view

When tirozinazo-negativnom glazo-kozhnom albinizme completely lacking melanin signs of the existence of an active and not synthesized tirozinaza. So, these people have white hair, pale pink skin, it is very sensitive to the solar rays, gray or bledno-golubuyu iris and fully depigmentirovannoe Eye bottom. This phenotype appears at birth and does not change over the life. Histological studies have shown that when tirozinazo-negativnom glazo-kozhnom albinizme melanotsity eye floor and epidermis are present in the normal number, but not accumulate melanin (87). However, reports in recent years (38, 59, 82) states that in electron microscopy bioptata iris collected from tirozinazo-negativnogo albinosa (not verifitsirovannogo biohimicheski), we noticed several melanosom fully mature. The authors asserted that because tirozinazy-catalytic function, the turning of melanine tirozina can happen and when tirozinazo-negativnom albinizme, although it will be very slow. Clinical experience gives grounds to assume that alleviation of view and photophobia, poor coloring and iris nystagmus more evident in this form albinizma than in others. U geterozigot tirozinazo-negativny glazo-kozhny albino can take bright color iris. Therefore bright coloring iris there can be an indicator for belokozhey among holders of the state population.

This is one of the most pervasive forms of Lose pigmentation Melanin. On autosomno-retsessivnomu inherited type. Its main characteristic - delayed start to look at pigmentation, as melanine slowly accumulated in the skin, hair and eyes over life. Test incubation hair bulb demonstrate that tirozinazy normal activity, and oral intake L-dopa not increase the overall level of pigmentation. This form is albinizma variety of phenotypic variation. The poignancy of view of the (ti-poz) albinos are usually somewhat higher than the tirozinazo-negativnoy form and ranges from 0.25 to 0.1. Studies have shown that block melanoproduktsii happening in the end-stages of education eumelaninaLose pigmentation Melanin.

In this form of activity albinizma Lose pigmentation Melaninthough present, but very few, and children, births without pigment, with the age acquire or zhelto-kremovuyu characteristic red coloring hair. As with other forms of true Lose pigmentation Melanin, patients suffer nistagmom and squint. The poignancy of view usually is not more than 0.1, but may be higher, particularly when the yellow mutant form albinizma melanin. These forms of inherited glazo-kozhnogo albinizma autosomno-retsessivnomu type and are not allelnymi gene variations tirozinazo-negativnogo albinizma Lose pigmentation Melanin.

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